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use "disassembly " in a sentence
Since 1951, 67,500 nuclear missiles have been built, of which 8,750 are currently active, and 1,250 are awaiting disassembly.
That is to say, the cell carries out a wide variety of molecular activities, including the turning on and o of transcription of genes into RNA, the processing of that RNA into mature messenger RNA, the translation of that RNA into proteins, the activities of many of those proteins as enzymes to catalyze reaction, the modification of the activities of enzymes by chemical events such as phosphorylation and dephosphorylation, the building of structural components such as bilipid membrane, and microtubule assembly and disassembly, and the construction of proteins and other receptors.
These include: quin2-AM (intracellular [Ca 2+]), herbimycin A (tyrosine kinases), chelerythrine (PKC), cytochalasin D (actin microfilaments), and nocodazole (disassembly of microtubules).
The results indicate that disassembly of cell-cell contacts between lens cells is not taking place, despite the forward movement of the lens cells into the ECM of the capsule.
Temporal and spatial regulation of this self-assembly and its associated disassembly process is critical for correct function.
The enzyme MHCK-A was subsequently purified to homogeneity and shown to be capable of driving myosin II filament disassembly in vitro via myosin II heavy chain phosphorylation [ 14 15 ] ).
Incubation of myosin II with MHCK-C in the presence of ATP resulted in substantial filament disassembly, with only 32% of the myosin II sedimenting following phosphorylation.
These results confirm that MHCK-C can phosphorylate myosin II, and that this phosphorylation is capable of driving filament disassembly in vitro.
MHCK-A may represent a factor that contributes to polar relaxation in this system via polar disassembly of myosin II filaments.
Although it is clear throughout the animal kingdom and in protozoa that the mass of myosin II in the division furrow decreases steadily with furrow ingression, no mechanism has been identified in any other system that can explain this regulated disassembly.
Dynamic changes in MHC phosphorylation levels within the contractile ring have been reported in dividing sea urchin embryos [ 35 ] , suggesting that MHC phosphorylation as a mechanism regulating furrow myosin II disassembly may occur in other systems besides D.
We suggest that MHCK-C participates in this regulated myosin II filament disassembly in D.
In previous work, when this method was applied to MHCK-A-expressing cell lines the elevated expression of MHCK-A resulted in myosin II hyperphosphorylation and myosin II filament disassembly, and corresponding loss of ability of cells to grow in suspension [ 24 ] .
The pTX-MKC2 plasmid was therefore transfected into 3xALA myosin II cells, which are resistant to myosin filament hyperphosphorylation and disassembly due to elimination of phosphorylation target sites in the myosin tail [ 24 ] .
Discussion Myosin-II localization is the result of a dynamic steady state in which recruitment is offset by thick filament disassembly.
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